{"type":"standard","title":"Rintodestrant","displaytitle":"Rintodestrant","namespace":{"id":0,"text":""},"wikibase_item":"Q131239122","titles":{"canonical":"Rintodestrant","normalized":"Rintodestrant","display":"Rintodestrant"},"pageid":78274310,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/9/9a/Rintodestrant.svg/330px-Rintodestrant.svg.png","width":320,"height":345},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/9/9a/Rintodestrant.svg/378px-Rintodestrant.svg.png","width":378,"height":408},"lang":"en","dir":"ltr","revision":"1260360811","tid":"9024d1a7-aeff-11ef-9cb3-f914c62a4b3d","timestamp":"2024-11-30T09:43:33Z","description":"Chemical compound","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Rintodestrant","revisions":"https://en.wikipedia.org/wiki/Rintodestrant?action=history","edit":"https://en.wikipedia.org/wiki/Rintodestrant?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Rintodestrant"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Rintodestrant","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Rintodestrant","edit":"https://en.m.wikipedia.org/wiki/Rintodestrant?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Rintodestrant"}},"extract":"Rintodestrant is an orally bioavailable selective estrogen receptor degrader (SERD) developed by G1 Therapeutics for the treatment of estrogen receptor-positive (ER+) breast cancer. Structurally inspired by the 6-OH-benzothiophene scaffold used in arzoxifene and raloxifene, rintodestrant selectively binds to the estrogen receptor and inhibits ER signaling, demonstrating efficacy in endocrine-resistant tumors.","extract_html":"
Rintodestrant is an orally bioavailable selective estrogen receptor degrader (SERD) developed by G1 Therapeutics for the treatment of estrogen receptor-positive (ER+) breast cancer. Structurally inspired by the 6-OH-benzothiophene scaffold used in arzoxifene and raloxifene, rintodestrant selectively binds to the estrogen receptor and inhibits ER signaling, demonstrating efficacy in endocrine-resistant tumors.
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